DrPKay.com

Franchina M, Kay PH.  DNMT1 Gene copy number does not influence susceptibility to malignant lymphoproliferative disease.  Anti-cancer Res 22:3405-7 (2002).

Pelham J. Irwin PJ, Kay PH.  Genomic hypomethylation in neoplastic cells from dogs with lymphoproliferative disorders. Res. Vet.Sci 74: 101-4 (2003).

Taylor JM, Kay PH, Spagnolo DV.  The diagnostic significance of Myf-3 hypermethylation in malignant lymphoproliferative disorders. Leukemia. 15:583-589 (2001).

Franchina M, Hooper J, Kay PH.  Five novel alternatively spliced transcripts of DNA (cytosine-5) methyltransferase2 in human peripheral blood leukocytes.  Int J of Biochem Cell Biol 33: 1104-1115 (2001).

Franchina M, Kay PH.  Novel nucleotide substitutions within the coding region of DNMT2 are in strong linkage disequilibrium in Caucasians and Japanese.  Hum Hered  52: 210-216 (2001).

Franchina M, Kay PH.  Evidence that cytosine residues within 5′-CCTGG-3′ pentanucleotides can be methylated in human DNA independently of the methylating system which modifies 5′-CG-3′ dinucleotides.  DNA Cell Biol 19:521-526 (2000).

Butler TL, Kay PH, Jacobsen, PF.  Hypomethylation of cytosine 5-methyltransferase in human neoplasms Anti-cancer Res 20:1435-1438 (2000).

Franchina M, Kay PH.  Allele-specific variation in the gene copy number of human cytosine 5-methyltransferase Hum Hered 50:112-117 (2000).

Rodger J, Ziman MR, Papadimitriou JM, Kay PH.  Pax7 is expressed in the capsules surrounding adult mouse neuromuscular spindles.  Biochem Cell Biol 77:153-156 (1999).

Kay PH, Ziman MR.  Alternate Pax7 paired box transcripts which include a trinucleotide or a hexanucleotide are generated by use of alternate 3′ intronic splice sites which are not utilised in the ancestral homolugue.  Gene 230:55-60 (1999).

Shannon B, Kay PH, House A, Iacopetta B.  Hypermethylation of the Myf-3 gene in colorectal cancers:  associations with pathological features and with microsatellite instability.  Int J Cancer 84:109-113 (1999).

Ziman MR, Kay PH.  A conserved TN8TCCT motif in the octopeptide encoding region of Pax genes which has the potential to direct cytosine methylation.  Gene 223:303-308 (1998).

Ziman MR, Kay PH.  Differential expression of four alternate Pax7 paired box transcripts is influenced by organ and strain specific factors in adult mice.  Gene 217.77-81 (1998).

Kay PH, Hahnel R, Gunn H, Harmon, Song J.  Hypermethylation of Hpall recognition sequences within the 5′ coding region of the estrogen receptor gene is not associated with estrogen receptor negativity in primary breast tumours.  Anti-cancer Res. 18:1709-1712 (1998).

Bagwe AN, Ahmed MO, Franchina M, Spagnolo DV, Papadimitriou JM, Kay PH.  A novel Msp1 PCR-RFLP in the human cytosine 5 methyltransferase gene: lack of relevance for malignant lymphoproliferative disease and breast cancer.  Hum Hered 48:226-229 (1998).

Kay PH, Harmon D, Fletcher S, Robertson T, Ziman M, Papadimitriou JM.  Pax7 includes two polymorphic homeoboxes which contain rearrangements associated with differences in the ability to regenerate damaged skeletal muscle in adult mice.  Int J Biochem Cell Biol 30:261-269 (1998).

Bagwe AN, Kay PH, Spagnolo DV.  Evidence that DNA methylation imbalance is not involved in the development of malignant mesothelioma.  Anticancer Research 17:3341-3344 (1997).

Taylor JM, Spagnolo DV, Kay PH.  B-cell target DNA quantity is a critical factor in the interpretation of B-cell clonality by PCR.  Pathology 29:309-312 (1997).

Ziman MR, Fletcher S, Kay PH.  Alternate Pax7 transcripts are expressed specifically in skeletal muscle, brain and other organs of adult mice.  Int J Biochem Cell Biol 29:1029-1036 (1997).

Kay PH, Harmon D, Fletcher S, Ziman M, Jacobsen PF, Papadimitriou JM.  Variation in the methylation profile and structure of Pax3 and Pax7 among different mouse strains and during expression.  Gene 184:45-53 (1997).

Kay PH, Spagnolo DV, Taylor J, Ziman M.  DNA methylation and developmental genes in lymphomagenesis - more questions than answers?  Leukemia Lymphoma 24:211-220 (1997).

Marlow SA, Kay PH, McGeachie JK, Papadimitriou JM.  Investigation of the influence of the Mm musculus Myo D1 allele on the efficiency of skeletal muscle regeneration . J Anat 190:223-227 (1997).

Iacopetta BJ, Harmon D, Spagnolo DV, House AK, Kay PH.  Hypermethylation of the Myf-3 gene in human colorectal cancer.  Anticancer Res 17:429-432 (1997).

Harmon D, Kay PH.  Polymorphism of Pax7 in the wild mouse gene pool.  Mouse Genome 94:868-870 (1996).

Hähnel R, Harvey J, Kay PH.  Hypermethylation of the myogenic gene Myf-3 in human breast carcinomas.  Anticancer Res 16:2111-2116 (1996).

Marlow SA, Kay PH, Papadimitriou JM.  Polymorphism of the mouse E2A gene due to an intronic deletion of 536 bp.  Gene 168:143-149 (1996).

Kay PH, Jacobsen PF, Taylor J, Spagnolo DV.  The significance of DNA methylation in cancer.  Adv Anat Path 2:353-361 (1995).

Lynch DM, Kay PH.  Studies on the polymorphism of the fifth component of complement in laboratory mice.  Exp Clin Immunogenet 12:253-260 (l995)

Kay PH, Mitchell CA, Akkari A, Papadimitriou JM.  Association of an unusual form of a Pax7-like gene with increased efficiency of skeletal muscle regeneration.  Gene 163:171-177 (1995).

Kay PH, Taylor J, Kees UR, Baker DL, Spagnolo DV.  Myf-3 hypermethylation in malignant lymphoproliferative disorders.  Int J Cancer 62:797-799 (1995).